Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC5R | P33032 | 2/20 | 0.73 |
| ▸ | MC3R | P41968 | 2/20 | 0.73 |
| ▸ | MC1R | Q01726 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | HTR2A | P28223 | 4/20 | 0.62 |
| ▸ | HTR6 | P50406 | 3/20 | 0.60 |
| ▸ | HTR1A | P08908 | 2/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.60 |
| ▸ | HTR7 | P34969 | 1/20 | 0.60 |
| ▸ | G6PD | P11413 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL830201 | 0.96 | MC5R (0.79) | MC5RMC3RMC1RKMT2AHTR2A | |
| Hydrochloric Acid SCHEMBL11188453 | 0.94 | MC5R (0.77) | MC5RMC3RMC1RKMT2AHTR2A | |
| SCHEMBL23745517 | 0.87 | MC5R (0.71) | MC5RMC3RMC1RKMT2AHTR2A | |
| Hydrochloric Acid SCHEMBL23722207 | 0.86 | MC5R (0.69) | MC5RMC3RMC1RKMT2AHTR2A | |
| SCHEMBL6635277 | 0.86 | SLC6A4 (0.67) | MC5RMC3RMC1RKMT2AHTR2A | |
| SCHEMBL6165432 | 0.85 | MC5R (0.71) | MC5RMC3RMC1RKMT2AHTR2A | |
| SCHEMBL798249 | 0.85 | MC1R (1.00) | MC5RMC3RMC1RKMT2AHTR2A | |
| SCHEMBL18088393 | 0.84 | MC5R (0.71) | MC5RMC3RMC1RKMT2AHTR2A | |
| SCHEMBL6037918 | 0.84 | MC5R (0.71) | MC5RMC3RMC1RKMT2AHTR2A | |
| SCHEMBL17117861 | 0.84 | MC5R (0.71) | MC5RMC3RMC1RKMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119775284-A | Five-membered double-spiro indoline derivative and preparation method and application thereof | 中苏圆科技集团有限公司 | 2025-04-08 | — | — | CN | claimed |
| CN-117924298-B | Spiro indolone derivative diastereomer and preparation method and application thereof | 苏州大学 | 2026-05-19 | — | — | CN | disclosed |
| CN-119775284-A | Five-membered double-spiro indoline derivative and preparation method and application thereof | 中苏圆科技集团有限公司 | 2025-04-08 | — | — | CN | disclosed |
| CN-117924298-A | Spiro indolone derivative diastereomer and preparation method and application thereof | 苏州大学 | 2024-04-26 | — | — | CN | disclosed |