Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC5R | P33032 | 2/20 | 0.71 |
| ▸ | MC3R | P41968 | 2/20 | 0.71 |
| ▸ | MC1R | Q01726 | 2/20 | 0.71 |
| ▸ | G6PD | P11413 | 1/20 | 0.70 |
| ▸ | HTR2A | P28223 | 4/20 | 0.69 |
| ▸ | HTR1A | P08908 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.63 |
| ▸ | BCHE | P06276 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HTR6 | P50406 | 2/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | HTR7 | P34969 | 1/20 | 0.58 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17232881 | 0.92 | MC5R (0.83) | MC5RMC3RMC1RG6PDHTR2A | |
| SCHEMBL7970552 | 0.90 | MC5R (0.81) | MC5RMC3RMC1RG6PDHTR2A | |
| SCHEMBL830201 | 0.89 | MC5R (0.79) | MC5RMC3RMC1RG6PDHTR2A | |
| SCHEMBL25342790 | 0.88 | MC5R (0.64) | MC5RMC3RMC1RG6PDHTR2A | |
| Hydrochloric Acid SCHEMBL11188453 | 0.88 | MC5R (0.77) | MC5RMC3RMC1RG6PDHTR2A | |
| Cyanide SCHEMBL30873705 | 0.85 | MC5R (0.73) | MC5RMC3RMC1RG6PDHTR2A | |
| SCHEMBL8524609 | 0.84 | MEN1 (0.70) | MC5RMC3RMC1RHTR2AHTR1A | |
| SCHEMBL14960999 | 0.84 | HTR2A (0.79) | MC5RMC3RMC1RG6PDHTR2A | |
| SCHEMBL4017867 | 0.84 | MC5R (0.71) | MC5RMC3RMC1RG6PDHTR2A | |
| SCHEMBL25029618 | 0.84 | MC5R (0.71) | MC5RMC3RMC1RG6PDHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1129070-A4 | NEUROTROPHIC DIAMIDE AND CARBAMATE AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2005-03-02 | — | — | EP | disclosed |
| EP-1129070-A1 | NEUROTROPHIC DIAMIDE AND CARBAMATE AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-09-05 | — | — | EP | disclosed |
| US-6228872-B1 | PEPTIDE-PROLYL ISOMERASE AND ROTAMASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2001-05-08 | — | — | US | disclosed |
| WO-2000027811-A1 | NEUROTROPHIC DIAMIDE AND CARBAMATE AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-05-18 | — | — | WO | disclosed |