Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC1R | Q01726 | 4/20 | 1.00 |
| ▸ | MC5R | P33032 | 3/20 | 1.00 |
| ▸ | MC3R | P41968 | 2/20 | 1.00 |
| ▸ | HTR2A | P28223 | 3/20 | 0.73 |
| ▸ | G6PD | P11413 | 1/20 | 0.69 |
| ▸ | HTR1A | P08908 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | HTR6 | P50406 | 3/20 | 0.64 |
| ▸ | DRD2 | P14416 | 1/20 | 0.64 |
| ▸ | HTR7 | P34969 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17232881 | 0.91 | MC5R (0.83) | MC1RMC5RMC3RHTR2AG6PD | |
| SCHEMBL7970552 | 0.89 | MC5R (0.81) | MC1RMC5RMC3RHTR2AG6PD | |
| SCHEMBL28268915 | 0.89 | MC5R (0.80) | MC1RMC5RMC3RHTR2AG6PD | |
| SCHEMBL830201 | 0.89 | MC5R (0.79) | MC1RMC5RMC3RHTR2AG6PD | |
| SCHEMBL28811757 | 0.88 | MC1R (0.78) | MC1RMC5RMC3RHTR2AG6PD | |
| SCHEMBL18770219 | 0.88 | MC5R (0.78) | MC1RMC5RMC3RHTR2AG6PD | |
| SCHEMBL878806 | 0.87 | MC1R (0.76) | MC1RMC5RMC3RHTR2AG6PD | |
| Hydrochloric Acid SCHEMBL11188453 | 0.87 | MC5R (0.77) | MC1RMC5RMC3RHTR2AG6PD | |
| SCHEMBL11922707 | 0.85 | MC1R (0.73) | MC1RMC5RMC3RHTR2AHTR1A | |
| SCHEMBL11344810 | 0.85 | MC5R (0.73) | MC1RMC5RMC3RHTR2AG6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616439-B1 | TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN GASTROPATHY | COUNCIL SCIENT IND RES (IN) | 2015-12-16 | — | — | EP | disclosed |
| US-8901317-B2 | Tryptamine derivatives, their preparation and their use in gastropathy | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-12-02 | — | — | US | disclosed |
| US-20130197052-A1 | TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN GASTROPATHY | UNIVERSITY OF CALCUTTA (IN) | 2013-08-01 | — | — | US | disclosed |
| EP-2616439-A1 | TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN GASTROPATHY | Council of Scientific & Industrial Research (IN) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035406-A1 | TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN GASTROPATHY | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130197052-A1 | TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN GASTROPATHY | HTRA2, AIFM1, SI | MC1R 1294/4885MC5R 1311/4885MC3R 448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.