Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31255572 | 0.92 | GAA (0.48) | MEN1KMT2AGAASOS1ALDH1A1 | |
| SCHEMBL24735010 | 0.91 | NR3C1 (0.47) | KMT2AALDH1A1POLBNR3C1PGR | |
| SCHEMBL29841507 | 0.91 | NR3C1 (0.47) | KMT2AALDH1A1POLBNR3C1PGR | |
| SCHEMBL21409416 | 0.91 | MEN1 (0.49) | MEN1KMT2AGAASOS1ALDH1A1 | |
| SCHEMBL31255318 | 0.91 | MEN1 (0.47) | MEN1KMT2AGAASOS1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29841613 | 0.90 | NR3C1 (0.46) | KMT2AALDH1A1POLBNR3C1PGR | |
| SCHEMBL31255602 | 0.89 | L3MBTL3 (0.44) | KMT2AALDH1A1POLBNR3C1PGR | |
| SCHEMBL31255457 | 0.88 | SOS1 (0.46) | MEN1KMT2AGAASOS1ALDH1A1 | |
| SCHEMBL31255603 | 0.88 | KDM4E (0.48) | ALDH1A1NR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL31255622 | 0.88 | SOS1 (0.44) | MEN1KMT2AGAASOS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118754858-A | N- (3- (7H-pyrrolo [2,3-d ] pyrimidin-4-yl) phenyl) benzamide derivatives | 诺华股份有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-111936498-B | N- (3- (7H-pyrrolo [2,3-d ] pyrimidin-4-yl) phenyl) benzamide derivatives | 诺华股份有限公司 | 2024-04-16 | — | — | CN | disclosed |