SCHEMBL31255602

SCHEMBL31255602

COc1ccc(C(=O)N2CCC(C3CCNCC3)CC2)cc1N1CCC(=O)NC1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL3 Q96JM7 1/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ NR3C1 P04150 1/20 0.43
▸ PGR P06401 1/20 0.43
▸ SLC6A4 P31645 1/20 0.43
▸ KCNH2 Q12809 1/20 0.43
▸ PDE3B Q13370 1/20 0.43
▸ PDE3A Q14432 1/20 0.43
▸ LMNA P02545 2/20 0.43
▸ HSD11B1 P28845 2/20 0.42
▸ ITGB3 P05106 3/20 0.41
▸ ITGA2B P08514 3/20 0.41
▸ ALDH1A1 P00352 4/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ CDK1 P06493 1/20 0.39
▸ CDK2 P24941 1/20 0.39
▸ CASP3 P42574 1/20 0.39
▸ GSK3B P49841 1/20 0.39
▸ CDK7 P50613 1/20 0.39
▸ CDK9 P50750 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21409448 0.91 HSD11B1 (0.42) NR3C1PGRSLC6A4KCNH2PDE3B
SCHEMBL29841507 0.91 NR3C1 (0.47) L3MBTL1NR3C1PGRSLC6A4KCNH2
SCHEMBL24735010 0.91 NR3C1 (0.47) L3MBTL1NR3C1PGRSLC6A4KCNH2
Hydrochloric Acid SCHEMBL30008988 0.91 HSD11B1 (0.41) NR3C1PGRSLC6A4KCNH2PDE3B
SCHEMBL30278909 0.91 NR3C1 (0.41) L3MBTL1NR3C1PGRSLC6A4KCNH2
Hydrochloric Acid SCHEMBL23122705 0.91 HSD11B1 (0.41) NR3C1PGRSLC6A4KCNH2PDE3B
Hydrochloric Acid SCHEMBL29841613 0.90 NR3C1 (0.46) L3MBTL1NR3C1PGRSLC6A4KCNH2
SCHEMBL31255603 0.89 KDM4E (0.48) L3MBTL3L3MBTL1NR3C1PGRSLC6A4
SCHEMBL30874152 0.89 MEN1 (0.47) L3MBTL1NR3C1PGRSLC6A4KCNH2
SCHEMBL31586070 0.88 NR3C1 (0.43) L3MBTL1NR3C1PGRSLC6A4KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720044-A1 AROMATIC AMIDES AND CONJUGATES THEREOF AS BINDERS TO TEAD Beactica Therapeutics AB (SE) 2026-04-08 — — EP disclosed
WO-2024240840-A1 AROMATIC AMIDES AND CONJUGATES THEREOF AS BINDERS TO TEAD BEACTICA THERAPEUTICS AB (SE) 2024-11-28 — — WO disclosed
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