Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.52 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29191056 | 1.00 | ALDH1A1 (0.59) | ALDH1A1GAALMNABAZ2BBAZ2A | |
| SCHEMBL10941698 | 0.89 | GPR17 (0.47) | ALDH1A1GAALMNABAZ2BBAZ2A | |
| SCHEMBL1149848 | 0.85 | ALDH1A1 (0.69) | ALDH1A1GAALMNABAZ2BBAZ2A | |
| SCHEMBL30874536 | 0.84 | ALDH1A1 (0.58) | ALDH1A1GAALMNABAZ2BBAZ2A | |
| SCHEMBL30874532 | 0.84 | L3MBTL1 (0.61) | ALDH1A1GAALMNABAZ2BBAZ2A | |
| SCHEMBL30874551 | 0.84 | ALDH1A1 (0.58) | ALDH1A1GAALMNABAZ2BBAZ2A | |
| SCHEMBL29190976 | 0.84 | L3MBTL1 (0.61) | ALDH1A1GAALMNABAZ2BBAZ2A | |
| SCHEMBL29191008 | 0.84 | ALDH1A1 (0.58) | ALDH1A1GAALMNABAZ2BBAZ2A | |
| SCHEMBL29190980 | 0.84 | ALDH1A1 (0.58) | ALDH1A1GAALMNABAZ2BBAZ2A | |
| SCHEMBL30874537 | 0.84 | SMN1; SMN2 (0.56) | ALDH1A1GAAL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117886734-A | Heterocyclic amide compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2024-04-16 | — | — | CN | disclosed |