Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | VNN1 | O95497 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29190945 | 1.00 | SMN1; SMN2 (0.56) | SMN1; SMN2RAB9ANPC1HSP90AA1PKM | |
| SCHEMBL10942146 | 0.88 | POLB (0.54) | SMN1; SMN2RAB9ANPC1HSP90AA1PKM | |
| SCHEMBL29191056 | 0.84 | ALDH1A1 (0.59) | SMN1; SMN2POLBALDH1A1MAPTGAA | |
| SCHEMBL30874543 | 0.84 | ALDH1A1 (0.59) | SMN1; SMN2POLBALDH1A1MAPTGAA | |
| SCHEMBL2419793 | 0.83 | ALDH1A1 (0.68) | SMN1; SMN2RAB9ANPC1HSP90AA1PKM | |
| SCHEMBL29190961 | 0.82 | SMN1; SMN2 (0.69) | SMN1; SMN2RAB9ANPC1HSP90AA1PKM | |
| SCHEMBL30874562 | 0.81 | RAB9A (0.52) | SMN1; SMN2RAB9ANPC1HSP90AA1PKM | |
| SCHEMBL30874540 | 0.81 | MAPK7 (0.57) | SMN1; SMN2RAB9ANPC1HSP90AA1PKM | |
| SCHEMBL29190944 | 0.81 | RAB9A (0.52) | SMN1; SMN2RAB9ANPC1HSP90AA1PKM | |
| SCHEMBL29191035 | 0.81 | MAPK7 (0.57) | SMN1; SMN2RAB9ANPC1HSP90AA1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117886734-A | Heterocyclic amide compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2024-04-16 | — | — | CN | disclosed |