Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | HTR1A | P08908 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10147158 | 0.88 | IGF1R (0.59) | IGF1RALDH1A1LMNAMAPTPOLB | |
| SCHEMBL10587768 | 0.85 | IGF1R (0.64) | IGF1RALDH1A1LMNAMAPTPOLB | |
| SCHEMBL4486168 | 0.85 | IGF1R (0.56) | IGF1RALDH1A1LMNAMAPTPOLB | |
| SCHEMBL4491439 | 0.85 | IGF1R (0.56) | IGF1RALDH1A1LMNAMAPTPOLB | |
| SCHEMBL19003598 | 0.85 | IGF1R (0.56) | IGF1RALDH1A1LMNAMAPTPOLB | |
| SCHEMBL12781849 | 0.84 | LMNA (0.68) | IGF1RALDH1A1LMNAMAPTPOLB | |
| SCHEMBL22639728 | 0.83 | HTR1A (0.57) | IGF1RALDH1A1LMNAMAPTPOLB | |
| SCHEMBL22639898 | 0.83 | HTR1A (0.57) | IGF1RALDH1A1LMNAMAPTPOLB | |
| Hydrochloric Acid SCHEMBL9493281 | 0.82 | LMNA (0.67) | IGF1RALDH1A1LMNAMAPTPOLB | |
| SCHEMBL7291269 | 0.82 | LMNA (0.67) | IGF1RALDH1A1LMNAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117886779-A | Piperazine alcohol compound with chiral hydroxyl, preparation method and medical application thereof | 徐州医科大学 | 2024-04-16 | — | — | CN | disclosed |