Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30874651 | 0.85 | IGF1R (0.64) | IGF1RLMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL12781849 | 0.84 | LMNA (0.68) | IGF1RLMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7291269 | 0.82 | LMNA (0.67) | IGF1RLMNAALDH1A1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9493281 | 0.82 | LMNA (0.67) | IGF1RLMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10147158 | 0.81 | IGF1R (0.59) | IGF1RLMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL14355262 | 0.79 | MEN1 (0.72) | LMNAALDH1A1MAPTSMN1; SMN2POLB | |
| SCHEMBL7297746 | 0.79 | POLB (0.59) | ALDH1A1MAPTPOLBHTR1AKDM4E | |
| SCHEMBL14067428 | 0.79 | SORD (0.60) | IGF1RALDH1A1MAPTPOLBHTR1A | |
| SCHEMBL19003598 | 0.79 | IGF1R (0.56) | IGF1RLMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4491439 | 0.79 | IGF1R (0.56) | IGF1RLMNAALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0319030-A1 | Aminopropanol derivatives of 1,4:3,6-dianhydro-hexitol nitrates, processes for their preparation and their use as medicaments | Heinrich Mack Nachf. (DE) | 1989-06-07 | — | — | EP | disclosed |