Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 12/20 | 0.40 |
| ▸ | HTR7 | P34969 | 12/20 | 0.40 |
| ▸ | MTOR | P42345 | 4/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30874924 | 0.88 | HTR1A (0.39) | HTR1AHTR7DPP4 | |
| SCHEMBL30874950 | 0.79 | DPP4 (0.42) | HTR1AHTR7DPP4 | |
| SCHEMBL30874930 | 0.76 | DPP4 (0.43) | HTR1AHTR7DPP4 | |
| SCHEMBL30874828 | 0.72 | DPP4 (0.40) | HTR1AHTR7DPP4 | |
| SCHEMBL30341409 | 0.69 | DPP4 (0.41) | HTR1AHTR7DPP4 | |
| SCHEMBL30874864 | 0.66 | VNN1 (0.47) | HTR1AHTR7DPP4 | |
| SCHEMBL30874847 | 0.66 | DPP4 (0.47) | HTR1AHTR7DPP4 | |
| SCHEMBL30874862 | 0.64 | CYP19A1 (0.47) | HTR1AHTR7DPP4 | |
| SCHEMBL1493753 | 0.64 | DPP4 (0.47) | HTR1AHTR7DPP4 | |
| SCHEMBL8772871 | 0.64 | DPP4 (0.56) | HTR1AHTR7DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117956985-A | Inhibitors of glycogen synthase 1 (GYS 1) and methods of use thereof | 梅兹治疗公司 | 2024-04-30 | — | — | CN | disclosed |