Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.35 |
| ▸ | ABAT | P80404 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16846737 | 1.00 | KIF11 (0.51) | KIF11ALDH1A1SMN1; SMN2PTGS2PTGS1 | |
| SCHEMBL18230875 | 0.86 | KIF11 (0.54) | KIF11ALDH1A1SMN1; SMN2PTGS2TSHR | |
| SCHEMBL13496965 | 0.84 | PTGS2 (0.43) | KIF11ALDH1A1SMN1; SMN2PTGS2PTGS1 | |
| SCHEMBL25512421 | 0.83 | PTGS1 (0.42) | KIF11ALDH1A1SMN1; SMN2PTGS2PTGS1 | |
| SCHEMBL14636222 | 0.83 | KIF11 (0.51) | KIF11ALDH1A1SMN1; SMN2PTGS2TSHR | |
| SCHEMBL29438427 | 0.82 | KIF11 (0.73) | KIF11ALDH1A1SMN1; SMN2PTGS2KDM4E | |
| SCHEMBL48409 | 0.82 | KIF11 (0.73) | KIF11ALDH1A1SMN1; SMN2PTGS2KDM4E | |
| SCHEMBL25187893 | 0.81 | KIF11 (0.46) | KIF11ALDH1A1PTGS2PTGS1CYP2A6 | |
| SCHEMBL11328597 | 0.81 | ALDH1A1 (0.42) | KIF11ALDH1A1PTGS2PTGS1TSHR | |
| SCHEMBL309292 | 0.80 | KIF11 (0.45) | KIF11ALDH1A1SMN1; SMN2PTGS2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117956985-A | Inhibitors of glycogen synthase 1 (GYS 1) and methods of use thereof | 梅兹治疗公司 | 2024-04-30 | — | — | CN | disclosed |