Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | VHL | P40337 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 5/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.36 |
| ▸ | CFD | P00746 | 4/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30874836 | 0.87 | CNR2 (0.37) | CNR2PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL30874917 | 0.81 | CNR2 (0.41) | CNR2PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL30874910 | 0.80 | CNR2 (0.39) | CNR2PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL30874812 | 0.78 | DPP4 (0.47) | CNR2PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL30341530 | 0.73 | DPP4 (0.46) | CNR2PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL10110426 | 0.72 | PIN1 (0.42) | CNR2PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL24664657 | 0.71 | CFD (0.36) | CFDITGA4 | |
| SCHEMBL24666074 | 0.70 | CFD (0.36) | CFDITGA4 | |
| SCHEMBL12757999 | 0.70 | PIN1 (0.40) | CNR2PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL1493709 | 0.70 | PIN1 (0.40) | CNR2PIK3CAPIK3CDPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117956985-A | Inhibitors of glycogen synthase 1 (GYS 1) and methods of use thereof | 梅兹治疗公司 | 2024-04-30 | — | — | CN | disclosed |