Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 5/20 | 0.46 |
| ▸ | ACE | P12821 | 4/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3103119 | 0.89 | FPR2 (0.54) | MMEACECPA1ACE2FPR2 | |
| SCHEMBL3090770 | 0.88 | ACE (0.44) | FOLH1MMEACECPA1ACE2 | |
| SCHEMBL29940571 | 0.82 | FOLH1 (0.50) | FOLH1MMEACECPA1ACE2 | |
| SCHEMBL2996598 | 0.80 | MME (0.56) | FOLH1MMEACENAALAD2CA1 | |
| SCHEMBL2989598 | 0.80 | MME (0.56) | FOLH1MMEACENAALAD2CA1 | |
| SCHEMBL3098284 | 0.79 | FPR2 (0.52) | FPR2CA1CA12CA9LNPEP | |
| SCHEMBL1287829 | 0.78 | FOLH1 (0.61) | FOLH1MMEACECPA1ACE2 | |
| SCHEMBL547122 | 0.78 | FOLH1 (0.61) | FOLH1MMEACECPA1ACE2 | |
| SCHEMBL547121 | 0.78 | FOLH1 (0.61) | FOLH1MMEACECPA1ACE2 | |
| SCHEMBL7413312 | 0.77 | MME (0.45) | MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |