Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3087564 | 0.88 | FOLH1 (0.47) | ACECA1CA12CA9ESR1 | |
| SCHEMBL3098284 | 0.88 | FPR2 (0.52) | CA1CA12CA9FPR2LNPEP | |
| SCHEMBL3103180 | 0.81 | PTPN2 (0.47) | ACECA1CA12CA9LNPEP | |
| SCHEMBL3103171 | 0.81 | PTPN2 (0.47) | ACECA1CA12CA9LNPEP | |
| SCHEMBL13910050 | 0.79 | ACE (0.52) | ACECA1CA12CA9FOLH1 | |
| SCHEMBL16217893 | 0.79 | ACE (0.52) | ACECA1CA12CA9FOLH1 | |
| SCHEMBL3103119 | 0.77 | FPR2 (0.54) | ACEFPR2MMECPA1ACE2 | |
| SCHEMBL3102568 | 0.77 | FPR2 (0.43) | FPR2LNPEPERAP2ERAP1 | |
| SCHEMBL3103505 | 0.76 | PPARD (0.40) | CA1CA12CA9FPR2CA2 | |
| SCHEMBL3097947 | 0.75 | TSHR (0.35) | CA1CA12CA9FPR2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |