Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 9/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 7/20 | 0.37 |
| ▸ | RAB9A | P51151 | 7/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30928762 | 0.78 | NPC1 (0.33) | TP53NPC1RAB9ATSHR | |
| SCHEMBL4431855 | 0.72 | WDR5 (0.44) | TP53HPGDHSD17B10WDR5ALDH1A1 | |
| SCHEMBL25060996 | 0.69 | WDR5 (0.44) | TP53HPGDHSD17B10WDR5ALDH1A1 | |
| SCHEMBL13455831 | 0.68 | WDR5 (0.46) | TP53HPGDHSD17B10WDR5ALDH1A1 | |
| SCHEMBL8883226 | 0.68 | LMNA (0.46) | TP53HPGDHSD17B10WDR5ALDH1A1 | |
| SCHEMBL29206946 | 0.67 | — | — | |
| SCHEMBL6078366 | 0.67 | — | — | |
| SCHEMBL31555683 | 0.66 | ALDH1A1 (0.33) | ALDH1A1KMT2A | |
| SCHEMBL7916624 | 0.65 | — | — | |
| SCHEMBL31015487 | 0.64 | PDE10A (0.36) | HPGDHSD17B10ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005606-A | TEAD inhibitors | 武汉人福创新药物研发中心有限公司 | 2024-05-10 | — | — | CN | disclosed |