Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 5/20 | 0.44 |
| ▸ | MMP9 | P14780 | 5/20 | 0.44 |
| ▸ | MMP13 | P45452 | 5/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.44 |
| ▸ | VNN1 | O95497 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.42 |
| ▸ | BMP1 | P13497 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29206926 | 1.00 | NAMPT (0.46) | NAMPTKDM4EMMP1MMP9MMP13 | |
| SCHEMBL29206993 | 0.91 | BMP1 (0.47) | KDM4EMMP1MMP9MMP13AURKA | |
| SCHEMBL30876228 | 0.91 | BMP1 (0.47) | KDM4EMMP1MMP9MMP13AURKA | |
| SCHEMBL29438855 | 0.87 | KDR (0.48) | NAMPTKDM4EMMP1MMP9MMP13 | |
| SCHEMBL22718052 | 0.87 | KDR (0.48) | NAMPTKDM4EMMP1MMP9MMP13 | |
| SCHEMBL24497433 | 0.82 | BMP1 (0.47) | NAMPTKDM4EMMP1MMP9MMP13 | |
| SCHEMBL30135124 | 0.82 | ALDH1A1 (0.41) | MMP9MMP13VNN1HDAC6MEN1 | |
| SCHEMBL29648392 | 0.81 | BMP1 (0.44) | KDM4EMMP1MMP9MMP13ADAM17 | |
| SCHEMBL24497371 | 0.81 | BMP1 (0.44) | KDM4EMMP1MMP9MMP13ADAM17 | |
| SCHEMBL30876291 | 0.78 | NAMPT (0.37) | NAMPTKDM4EMMP1MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005606-A | TEAD inhibitors | 武汉人福创新药物研发中心有限公司 | 2024-05-10 | — | — | CN | disclosed |