Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | KIF11 | P52732 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 3/20 | 0.35 |
| ▸ | GABRD | O14764 | 3/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12800982 | 1.00 | TOP2A (0.40) | TOP2AAHRALDH1A1HSD17B10GPR3 | |
| SCHEMBL15631669 | 0.94 | KDM4E (0.35) | TOP2AAHRALDH1A1HSD17B10KDM4E | |
| SCHEMBL23219318 | 0.92 | TOP2A (0.40) | TOP2AAHRALDH1A1HSD17B10GPR3 | |
| SCHEMBL26342598 | 0.85 | CDK4 (0.36) | TOP2AALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL18830921 | 0.83 | TOP2A (0.36) | TOP2AAHRALDH1A1HSD17B10GPR3 | |
| SCHEMBL18687112 | 0.83 | HPGD (0.37) | TOP2AAHRALDH1A1HSD17B10KDM4E | |
| SCHEMBL18698129 | 0.83 | HPGD (0.37) | TOP2AAHRALDH1A1HSD17B10KDM4E | |
| SCHEMBL20616762 | 0.82 | TOP2A (0.41) | TOP2AAHRALDH1A1HSD17B10GPR3 | |
| SCHEMBL18934348 | 0.82 | TOP2A (0.41) | TOP2AAHRALDH1A1HSD17B10GPR3 | |
| SCHEMBL23652412 | 0.82 | ADORA2B (0.35) | TOP2AAHRALDH1A1HSD17B10GPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024033282-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2024-02-15 | — | — | WO | disclosed |