Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 9/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12800982 | 0.92 | TOP2A (0.40) | TOP2AAHRKIF11ALDH1A1HSD17B10 | |
| SCHEMBL30876355 | 0.92 | TOP2A (0.40) | TOP2AAHRKIF11ALDH1A1HSD17B10 | |
| SCHEMBL26342598 | 0.87 | CDK4 (0.36) | TOP2AALDH1A1HSD17B10KDM4ETP53 | |
| SCHEMBL15631669 | 0.86 | KDM4E (0.35) | TOP2AAHRALDH1A1HSD17B10AURKA | |
| SCHEMBL20540671 | 0.85 | KIF11 (0.38) | KIF11ALDH1A1HSD17B10TP53HPGD | |
| SCHEMBL20448094 | 0.83 | ALDH1A1 (0.37) | TOP2AAHRKIF11ALDH1A1HSD17B10 | |
| SCHEMBL20616762 | 0.82 | TOP2A (0.41) | TOP2AAHRKIF11ALDH1A1HSD17B10 | |
| SCHEMBL18934348 | 0.82 | TOP2A (0.41) | TOP2AAHRKIF11ALDH1A1HSD17B10 | |
| SCHEMBL18934354 | 0.81 | AHR (0.41) | TOP2AAHRKIF11ALDH1A1HSD17B10 | |
| SCHEMBL18934858 | 0.81 | AHR (0.41) | TOP2AAHRKIF11ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230309379-A1 | LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE ORGANOMETALLIC COMPOUND | SAMSUNG DISPLAY CO., LTD. (KR) | 2023-09-28 | — | — | US | disclosed |
| US-20230309379-A1 | LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE ORGANOMETALLIC COMPOUND | SAMSUNG DISPLAY CO., LTD. (KR) | 2023-09-28 | — | — | US | disclosed |
| US-20220119434-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2022-04-21 | — | — | US | disclosed |
| US-10975113-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2021-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220119434-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | L1CAM, SOD1, EPCAM | TOP2A 3065/4885AHR 2874/4885KIF11 2948/4885 |
| US-10975113-B2 | Organic electroluminescent materials and devices | OSBPL3, OCIAD1, OSBP | TOP2A 3502/4885AHR 3316/4885KIF11 3269/4885 |
| US-20230309379-A1 | LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE ORGANOMETALLIC COMPOUND | CRY1, LEF1, LAGE3 | TOP2A 4429/4885AHR 1765/4885KIF11 2861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.