Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.36 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20616762 | 1.00 | TOP2A (0.41) | TOP2AAHRMAPK1HTTPDE7A | |
| SCHEMBL18934858 | 0.86 | AHR (0.41) | TOP2AAHRPDE7APDE7BKDM4E | |
| SCHEMBL18934354 | 0.86 | AHR (0.41) | TOP2AAHRPDE7APDE7BKDM4E | |
| SCHEMBL18698129 | 0.86 | HPGD (0.37) | TOP2AAHRMAPK1HTTPDE7A | |
| SCHEMBL18687112 | 0.86 | HPGD (0.37) | TOP2AAHRMAPK1HTTPDE7A | |
| SCHEMBL20448094 | 0.86 | ALDH1A1 (0.37) | TOP2AAHRMAPK1HTTPDE7A | |
| SCHEMBL23219318 | 0.82 | TOP2A (0.40) | TOP2AAHRKDM4EHSD17B10MAPT | |
| SCHEMBL12800982 | 0.82 | TOP2A (0.40) | TOP2AAHRKDM4EHSD17B10MAPT | |
| SCHEMBL30876355 | 0.82 | TOP2A (0.40) | TOP2AAHRKDM4EHSD17B10MAPT | |
| SCHEMBL18934334 | 0.81 | MAPK1 (0.50) | MAPK1HTTKDM4EHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11174258-B2 | Benzimidazolo[1,2-a]benzimidazole derivatives for organic light emitting diodes | IDEMITSU KOSAN CO., LTD. (JP) | 2021-11-16 | — | — | US | disclosed |
| US-20190002469-A1 | BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ORGANIC LIGHT EMITTING DIODES | IDEMITSU KOSAN CO., LTD. (JP) | 2019-01-03 | — | — | US | disclosed |
| WO-2017093958-A1 | BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ORGANIC LIGHT EMITTING DIODES | IDEMITSU KOSAN CO., LTD. (JP) | 2017-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11174258-B2 | Benzimidazolo[1,2-a]benzimidazole derivatives for organic light emitting diodes | KCNH2, KCNH3, KCNJ2 | TOP2A 2653/4885AHR 2264/4885MAPK1 2877/4885 |
| US-20190002469-A1 | BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ORGANIC LIGHT EMITTING DIODES | KCNH2, KCNH3, KCNJ2 | TOP2A 2653/4885AHR 2264/4885MAPK1 2877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.