Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 8/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CASP2 | P42575 | 2/20 | 0.33 |
| ▸ | CASP7 | P55210 | 2/20 | 0.33 |
| ▸ | CASP6 | P55212 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1256987 | 0.77 | KDM4E (0.40) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL2760791 | 0.77 | ELANE (0.40) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL9136212 | 0.75 | ALDH1A1 (0.38) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL15942346 | 0.74 | ALDH1A1 (0.47) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL10384426 | 0.74 | KDM4E (0.40) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL23142622 | 0.74 | KDM4E (0.42) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL15942344 | 0.73 | CASP3 (0.50) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL8074204 | 0.73 | POLB (0.37) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL6033869 | 0.72 | KDM4E (0.38) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL10731506 | 0.72 | CYSLTR2 (0.39) | KDM4EALDH1A1GAAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4611798-A1 | METHODS OF TREATMENT WITH T CELL THERAPY AND IMMUNOMODULATORY AGENT MAINTENANCE THERAPY | CELGENE CORPORATION (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024097905-A1 | METHODS OF TREATMENT WITH T CELL THERAPY AND IMMUNOMODULATORY AGENT MAINTENANCE THERAPY | CELGENE CORPORATION (US) | 2024-05-10 | — | — | WO | disclosed |