Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30877505 | 0.90 | KLK7 (0.34) | GRM5KDM1AALDH1A1NPSR1MCOLN3 | |
| SCHEMBL30877474 | 0.84 | RAPGEF4 (0.41) | TTKALDH1A1NPSR1JAK2JAK1 | |
| SCHEMBL30877417 | 0.83 | PIM1 (0.38) | TTKGRM5KDM1AALDH1A1NPSR1 | |
| SCHEMBL30877411 | 0.81 | BRD4 (0.38) | ALDH1A1NPSR1MCOLN3KLK7BRD4 | |
| SCHEMBL29131767 | 0.80 | ALDH1A1 (0.40) | ALDH1A1NPSR1MCOLN3KLK7BRD4 | |
| SCHEMBL30877365 | 0.80 | ALDH1A1 (0.35) | ALDH1A1NPSR1MCOLN3BRD4 | |
| SCHEMBL30877292 | 0.79 | BRD4 (0.35) | ALDH1A1NPSR1MCOLN3JAK2JAK1 | |
| SCHEMBL30877513 | 0.79 | KIT (0.37) | KDM1AALDH1A1NPSR1MCOLN3BRD4 | |
| SCHEMBL30877414 | 0.79 | KIT (0.37) | KDM1AALDH1A1NPSR1MCOLN3BRD4 | |
| SCHEMBL30877239 | 0.77 | BRD4 (0.41) | GRM5ALDH1A1NPSR1MCOLN3KLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964643-B | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117964643-A | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-05-03 | — | — | CN | disclosed |