Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K7 | O43318 | 12/20 | 0.44 |
| ▸ | TAB1 | Q15750 | 12/20 | 0.44 |
| ▸ | MET | P08581 | 2/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.41 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.40 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.40 |
| ▸ | KHK | P50053 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30877321 | 0.89 | RAPGEF4 (0.43) | — | |
| SCHEMBL30877343 | 0.88 | HTR6 (0.46) | BMPR1AACVRL1ACVR1 | |
| SCHEMBL30877483 | 0.86 | RAPGEF4 (0.35) | MAP3K7TAB1 | |
| SCHEMBL30877294 | 0.85 | MAP3K7 (0.45) | MAP3K7TAB1METKHK | |
| SCHEMBL30877312 | 0.84 | CYP1A2 (0.46) | METJAK3KHK | |
| SCHEMBL30877450 | 0.82 | RAPGEF4 (0.41) | — | |
| SCHEMBL30877358 | 0.78 | RAPGEF4 (0.37) | — | |
| SCHEMBL30877392 | 0.77 | RAPGEF4 (0.48) | — | |
| SCHEMBL30877309 | 0.74 | RAPGEF4 (0.45) | — | |
| SCHEMBL30877239 | 0.72 | BRD4 (0.41) | METTYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964643-B | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117964643-A | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-05-03 | — | — | CN | disclosed |