Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K7 | O43318 | 13/20 | 0.45 |
| ▸ | TAB1 | Q15750 | 13/20 | 0.45 |
| ▸ | MET | P08581 | 5/20 | 0.43 |
| ▸ | KHK | P50053 | 1/20 | 0.41 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30877239 | 0.89 | BRD4 (0.41) | METPAK1 | |
| SCHEMBL30877241 | 0.89 | MET (0.39) | METKHKPAK1 | |
| SCHEMBL30877512 | 0.86 | KRAS (0.35) | MAP3K7TAB1METKHK | |
| SCHEMBL30877421 | 0.85 | MAP3K7 (0.44) | MAP3K7TAB1METKHK | |
| SCHEMBL30877371 | 0.85 | CHRNB2 (0.44) | METKHKPAK1 | |
| SCHEMBL30877417 | 0.82 | PIM1 (0.38) | — | |
| SCHEMBL30877467 | 0.79 | GRM5 (0.34) | MET | |
| SCHEMBL29131767 | 0.78 | ALDH1A1 (0.40) | — | |
| SCHEMBL30877402 | 0.75 | ALDH1A1 (0.38) | — | |
| SCHEMBL30877387 | 0.73 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964643-B | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117964643-A | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-05-03 | — | — | CN | disclosed |