Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 4/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL929124 | 0.82 | CHRNA7 (0.44) | CHRNB4CHRNA3CNR2CHRNA7KCNH2 | |
| SCHEMBL20157231 | 0.72 | CHRNB4 (0.49) | CHRNB4CHRNA3 | |
| SCHEMBL20071406 | 0.72 | CHRNB4 (0.46) | RETCHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL23607827 | 0.71 | CHRNB4 (0.45) | RETCHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL25222660 | 0.71 | CHRNB4 (0.45) | RETCHRNB4CHRNA3 | |
| SCHEMBL20071399 | 0.65 | CHRNB4 (0.57) | RETCHRNB4CHRNA3 | |
| SCHEMBL13103511 | 0.65 | CHRNB2 (0.51) | RETCHRNB4CHRNA3 | |
| SCHEMBL21262167 | 0.65 | CHRNB2 (0.59) | RETCHRNB4CHRNA3CNR2 | |
| SCHEMBL21262008 | 0.65 | CHRNB2 (0.59) | RETCHRNB4CHRNA3CNR2 | |
| SCHEMBL20468889 | 0.65 | CHRNB2 (0.51) | RETCHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964643-B | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117964643-A | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-05-03 | — | — | CN | disclosed |