Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18355724 | 0.70 | ALDH1A1 (0.47) | LMNAALDH1A1MITFHTTTRPM8 | |
| SCHEMBL20325708 | 0.68 | CYP1A2 (0.48) | ALDH1A1CASP1HSD17B10 | |
| SCHEMBL1269070 | 0.68 | MAPT (0.43) | LMNAALDH1A1TRPM8TSHRKMT2A | |
| SCHEMBL14380666 | 0.67 | LMNA (0.51) | LMNAALDH1A1MITFHTTTSHR | |
| SCHEMBL8203306 | 0.65 | LMNA (0.40) | LMNAALDH1A1MITFHTTTRPM8 | |
| SCHEMBL20234660 | 0.65 | ALDH1A1 (0.47) | ALDH1A1TSHRKMT2AKDM4EMAPK1 | |
| SCHEMBL13285784 | 0.65 | KMT2A (0.50) | LMNAALDH1A1HTTTSHRKMT2A | |
| SCHEMBL13146350 | 0.64 | LMNA (0.36) | LMNAALDH1A1MITFHTTTRPM8 | |
| SCHEMBL2820755 | 0.63 | LMNA (0.35) | LMNAALDH1A1MITFHTTTRPM8 | |
| SCHEMBL5728 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964643-B | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117964643-A | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-05-03 | — | — | CN | disclosed |