Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1269070 | 0.84 | MAPT (0.43) | LMNAMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL20234660 | 0.81 | ALDH1A1 (0.47) | KMT2AALDH1A1TSHRKDM4ECYP1A2 | |
| SCHEMBL13285784 | 0.81 | KMT2A (0.50) | LMNAMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL20325708 | 0.79 | CYP1A2 (0.48) | ALDH1A1CYP1A2 | |
| SCHEMBL20234338 | 0.75 | MAPT (0.47) | MEN1KMT2AALDH1A1TSHRKDM4E | |
| SCHEMBL2004023 | 0.70 | MAPT (0.46) | NPC1MAPTRAB9A | |
| SCHEMBL13622722 | 0.69 | FFAR4 (0.43) | KDM4E | |
| SCHEMBL30877458 | 0.65 | LMNA (0.42) | LMNAMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL18355724 | 0.65 | ALDH1A1 (0.47) | LMNAMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL27920493 | 0.65 | SORD (0.50) | LMNAKMT2AALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110939-A | AS A SUBSTANCE P ANTAGONISTS TREATING TACHYKININ-MEDIATED DISEASE, ASTHMA, CENTRAL NERVOUS SYSTEM DISORDER | JANSSEN PHARMACEUTICA N.V. (BE) | 2000-08-29 | — | — | US | disclosed |