Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.33 |
| ▸ | MYLK | Q15746 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14989204 | 1.00 | LMNA (0.42) | LMNAKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL24487924 | 0.84 | LMNA (0.38) | LMNAKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL28347722 | 0.81 | DGAT1 (0.34) | KDM4EALDH1A1POLBHPGD | |
| SCHEMBL20489645 | 0.81 | LMNA (0.36) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL26026626 | 0.80 | IDO1 (0.31) | — | |
| SCHEMBL21257301 | 0.79 | NPC1 (0.39) | LMNAKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL20489606 | 0.78 | LMNA (0.38) | LMNAALDH1A1NPC1RAB9APOLB | |
| SCHEMBL22575343 | 0.77 | LMNA (0.36) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11966906 | 0.77 | NOS3 (0.41) | ALDH1A1MAPTTDP1RAB9ANPSR1 | |
| SCHEMBL30696909 | 0.77 | NOS3 (0.41) | ALDH1A1MAPTTDP1RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4608401-A2 | MK2 INHIBITORS AND USES THEREOF | Bristol-Myers Squibb Company (US) | 2025-09-03 | — | — | EP | disclosed |
| CN-119894879-A | Tyrosine kinase 2 inhibitors and uses thereof | 渤健马萨诸塞州股份有限公司 | 2025-04-25 | — | — | CN | disclosed |
| WO-2024092115-A2 | MK2 INHIBITORS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-05-02 | — | — | WO | disclosed |