Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ITK | Q08881 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33530556 | 0.95 | RIPK1 (0.46) | RIPK1PDK2CA12CA1CA2 | |
| SCHEMBL30878583 | 0.76 | CA12 (0.47) | PDK2CA12CA1CA2CA9 | |
| SCHEMBL21540828 | 0.74 | PDK2 (0.57) | PDK2CA12CA1CA2CA9 | |
| SCHEMBL14836086 | 0.74 | CHRNA3 (0.45) | CA12CA1CA2CA9 | |
| SCHEMBL14836085 | 0.74 | CHRNA3 (0.45) | CA12CA1CA2CA9 | |
| SCHEMBL30878596 | 0.74 | PDK2 (0.48) | PDK2CA12CA1CA2CA9 | |
| SCHEMBL23729233 | 0.73 | CA12 (0.57) | PDK2CA12CA1CA2CA9 | |
| SCHEMBL30441709 | 0.73 | CA12 (0.57) | PDK2CA12CA1CA2CA9 | |
| SCHEMBL28907805 | 0.73 | RIPK1 (0.50) | RIPK1ALDH1A1TDP1 | |
| SCHEMBL30878515 | 0.73 | RIPK1 (0.45) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587126-A1 | COMPOUNDS FOR TARGETED PROTEIN DEGRADATION | Amphista Therapeutics Ltd (GB) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024057021-A1 | COMPOUNDS FOR TARGETED PROTEIN DEGRADATION | AMPHISTA THERAPEUTICS LIMITED (GB) | 2024-03-21 | — | — | WO | disclosed |