Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 11/20 | 0.49 |
| ▸ | L3MBTL3 | Q96JM7 | 11/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | GFER | P55789 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL520612 | 0.84 | MAPT (0.50) | L3MBTL1L3MBTL3MAPTGFERKDM4E | |
| SCHEMBL16445747 | 0.83 | L3MBTL1 (0.53) | L3MBTL1L3MBTL3MAPTGFERKDM4E | |
| Hydrochloric Acid SCHEMBL3566395 | 0.82 | MAPT (0.53) | L3MBTL1L3MBTL3MAPTGFERKDM4E | |
| SCHEMBL30879285 | 0.81 | MAPT (0.45) | L3MBTL1L3MBTL3MAPTGFERKDM4E | |
| SCHEMBL15651591 | 0.81 | MAPT (0.43) | L3MBTL1MAPTGFERKDM4EGAA | |
| SCHEMBL13735219 | 0.81 | MAPT (0.43) | L3MBTL1MAPTGFERKDM4EGAA | |
| SCHEMBL15652597 | 0.81 | MAPT (0.43) | L3MBTL1MAPTGFERKDM4EGAA | |
| SCHEMBL23983401 | 0.80 | MAPT (0.44) | L3MBTL1MAPTGFERKDM4EGAA | |
| SCHEMBL2236451 | 0.77 | L3MBTL3 (0.81) | L3MBTL1L3MBTL3MAPTGFERKDM4E | |
| SCHEMBL16446432 | 0.77 | L3MBTL1 (0.50) | L3MBTL1L3MBTL3MAPTGFERKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612148-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | Cancer Research Technology Limited (GB) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024094963-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-05-10 | — | — | WO | disclosed |