Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30879993 | 0.81 | USP30 (0.44) | RIPK1NR1H2NR1H3LCKJAK3 | |
| SCHEMBL17067870 | 0.75 | RIPK1 (0.73) | RIPK1NR1H2NR1H3UCHL1 | |
| SCHEMBL469686 | 0.75 | RIPK1 (0.73) | RIPK1NR1H2NR1H3UCHL1 | |
| SCHEMBL17067869 | 0.75 | RIPK1 (0.73) | RIPK1NR1H2NR1H3UCHL1 | |
| SCHEMBL31342245 | 0.75 | NR1H2 (0.37) | RIPK1NR1H2NR1H3TP53HPGDS | |
| SCHEMBL35211570 | 0.75 | NR1H2 (0.37) | RIPK1NR1H2NR1H3TP53HPGDS | |
| SCHEMBL13118692 | 0.75 | FAAH (0.48) | NR1H2NR1H3GRM5GRM1GPR119 | |
| SCHEMBL22772747 | 0.75 | FAAH (0.48) | NR1H2NR1H3GRM5GRM1GPR119 | |
| SCHEMBL19897208 | 0.75 | RIPK1 (0.56) | RIPK1NR1H2NR1H3GPR119UCHL1 | |
| SCHEMBL19897255 | 0.75 | RIPK1 (0.56) | RIPK1NR1H2NR1H3GPR119UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4608807-A1 | PROTEIN DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2025-09-03 | — | — | EP | disclosed |
| WO-2025090412-A1 | DCAF1 LIGANDS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2025-05-01 | — | — | WO | disclosed |
| WO-2024092009-A1 | PROTEIN DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-05-02 | — | — | WO | disclosed |
| WO-2024092011-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-05-02 | — | — | WO | disclosed |