Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PLEC | Q15149 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22721887 | 1.00 | TSHR (0.51) | TSHRGLAGAAHPGDCYP1A2 | |
| SCHEMBL22721901 | 0.73 | TSHR (0.67) | TSHRGAAHPGDKDM4EMEN1 | |
| SCHEMBL30880198 | 0.73 | TSHR (0.67) | TSHRGAAHPGDKDM4EMEN1 | |
| SCHEMBL22721888 | 0.73 | TSHR (0.67) | TSHRGAAHPGDKDM4EMEN1 | |
| SCHEMBL11418228 | 0.70 | CYP1A2 (0.66) | TSHRGAAHPGDCYP1A2CYP3A4 | |
| SCHEMBL4059494 | 0.70 | TSHR (0.45) | TSHRGAAHPGDCYP1A2CYP3A4 | |
| SCHEMBL265111 | 0.69 | TSHR (1.00) | TSHRGAAHPGDCYP1A2CYP3A4 | |
| SCHEMBL31384289 | 0.69 | TSHR (1.00) | TSHRGAAHPGDCYP1A2CYP3A4 | |
| SCHEMBL20268413 | 0.68 | ALDH1A1 (0.51) | GLAGAAKDM4EMEN1KMT2A | |
| SCHEMBL22552200 | 0.68 | NOX4 (0.42) | TSHRGAAHPGDCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113840820-B | Phthalazinone compounds and uses thereof | ST制药株式会社 | 2024-05-03 | — | — | CN | disclosed |