Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.59 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30880594 | 1.00 | CYP11B1 (0.59) | CYP11B1CYP11B2LMNAMAPTMAOA | |
| SCHEMBL31138008 | 0.88 | CYP11B1 (0.68) | CYP11B1CYP11B2LMNAMAPTMAOA | |
| SCHEMBL14483736 | 0.88 | CYP11B1 (0.68) | CYP11B1CYP11B2LMNAMAPTMAOA | |
| SCHEMBL30050066 | 0.81 | CYP11B1 (0.59) | CYP11B1CYP11B2LMNAMAPTMAOA | |
| SCHEMBL29186518 | 0.81 | CYP11B1 (0.59) | CYP11B1CYP11B2LMNAMAPTMAOA | |
| SCHEMBL9609628 | 0.78 | LMNA (0.55) | CYP11B1CYP11B2LMNAMAPTCYP19A1 | |
| SCHEMBL30880680 | 0.78 | LMNA (0.55) | CYP11B1CYP11B2LMNAMAPTCYP19A1 | |
| SCHEMBL285074 | 0.78 | CYP11B1 (0.73) | CYP11B1CYP11B2LMNAMAPTMAOA | |
| SCHEMBL8333311 | 0.77 | CYP11B1 (0.55) | CYP11B1CYP11B2LMNAMAPTMAOA | |
| SCHEMBL6389607 | 0.77 | CYP11B1 (0.71) | CYP11B1CYP11B2LMNAMAPTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024078513-A1 | CONDENSED AZINES FOR TREATING CANCER | CHENGDU ANTICANCER BIOSCIENCE , LTD. (CN) | 2024-04-18 | — | — | WO | disclosed |