Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9609628 | 1.00 | LMNA (0.55) | LMNAMAPTCYP3A4TSHRALDH1A1 | |
| SCHEMBL872411 | 0.91 | LMNA (0.53) | LMNAMAPTCYP3A4TSHRCYP11B1 | |
| SCHEMBL18288736 | 0.87 | CYP3A4 (0.52) | LMNAMAPTCYP3A4TSHRCYP11B1 | |
| SCHEMBL10760976 | 0.79 | LMNA (0.41) | LMNAMAPTCYP3A4CYP11B1CYP11B2 | |
| SCHEMBL25492424 | 0.79 | ENPP2 (0.55) | LMNAMAPTCYP3A4TSHRALDH1A1 | |
| SCHEMBL18282264 | 0.79 | CYP11B1 (0.47) | LMNAMAPTCYP3A4TSHRCYP11B1 | |
| SCHEMBL30880594 | 0.78 | CYP11B1 (0.59) | LMNAMAPTCYP3A4CYP11B1CYP11B2 | |
| SCHEMBL30880480 | 0.78 | CYP11B1 (0.59) | LMNAMAPTCYP3A4CYP11B1CYP11B2 | |
| SCHEMBL15315529 | 0.76 | MAP3K5 (0.42) | LMNAMAPTCYP3A4TSHRALDH1A1 | |
| SCHEMBL16673120 | 0.76 | CYP3A4 (0.62) | LMNAMAPTCYP3A4TSHRCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024078513-A1 | CONDENSED AZINES FOR TREATING CANCER | CHENGDU ANTICANCER BIOSCIENCE , LTD. (CN) | 2024-04-18 | — | — | WO | disclosed |