Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKE | Q14164 | 6/20 | 0.44 |
| ▸ | TBK1 | Q9UHD2 | 6/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30880554 | 0.92 | JAK2 (0.44) | IKBKETBK1FEN1JAK2LOXL2 | |
| SCHEMBL30880662 | 0.86 | KIT (0.47) | IKBKETBK1LOXL2FGFR1FGFR2 | |
| SCHEMBL30880741 | 0.83 | KDR (0.42) | JAK2LOXL2FGFR1FGFR2FGFR4 | |
| SCHEMBL30880509 | 0.79 | FGFR1 (0.49) | IKBKEFEN1LOXL2FGFR1FGFR2 | |
| SCHEMBL14321130 | 0.79 | FEN1 (0.49) | IKBKETBK1FEN1JAK2PIK3CD | |
| SCHEMBL1663037 | 0.74 | MEN1 (0.45) | IKBKETBK1FEN1JAK2BACE1 | |
| Hydrochloric Acid SCHEMBL28364565 | 0.73 | MEN1 (0.44) | IKBKETBK1FEN1JAK2BACE1 | |
| SCHEMBL30839799 | 0.72 | ALDH1A1 (0.50) | TDP1 | |
| SCHEMBL27185954 | 0.72 | ALDH1A1 (0.50) | TDP1 | |
| SCHEMBL30880622 | 0.71 | LOXL2 (0.53) | LOXL2FGFR1FGFR2FGFR3PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024078513-A1 | CONDENSED AZINES FOR TREATING CANCER | CHENGDU ANTICANCER BIOSCIENCE , LTD. (CN) | 2024-04-18 | — | — | WO | disclosed |