Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.47 |
| ▸ | FGFR3 | P22607 | 11/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 11/20 | 0.44 |
| ▸ | KDR | P35968 | 9/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 6/20 | 0.44 |
| ▸ | FGFR4 | P22455 | 6/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | INSR | P06213 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | LYN | P07948 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | FER | P16591 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | FRK | P42685 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30880679 | 0.86 | IKBKE (0.44) | FGFR3FGFR1KDRFGFR2FGFR4 | |
| SCHEMBL30880554 | 0.84 | JAK2 (0.44) | PDK2FGFR3FGFR1KDRFGFR2 | |
| SCHEMBL30880741 | 0.83 | KDR (0.42) | FGFR3FGFR1KDRFGFR2FGFR4 | |
| SCHEMBL30880509 | 0.82 | FGFR1 (0.49) | KITPDK2FGFR3FGFR1KDR | |
| SCHEMBL11827587 | 0.79 | MEN1 (0.58) | KITPDK2FGFR3FGFR1KDR | |
| SCHEMBL19537419 | 0.72 | KIT (0.48) | KITPDK2METPRMT5WDR77 | |
| SCHEMBL27185954 | 0.72 | ALDH1A1 (0.50) | KITABL1NTRK1 | |
| SCHEMBL30839799 | 0.72 | ALDH1A1 (0.50) | KITABL1NTRK1 | |
| SCHEMBL30880622 | 0.71 | LOXL2 (0.53) | FGFR3FGFR1FGFR2LOXL2 | |
| SCHEMBL30880676 | 0.69 | ROCK2 (0.46) | KITFGFR3FGFR1FGFR2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024078513-A1 | CONDENSED AZINES FOR TREATING CANCER | CHENGDU ANTICANCER BIOSCIENCE , LTD. (CN) | 2024-04-18 | — | — | WO | disclosed |