Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | OGG1 | O15527 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17676467 | 0.92 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1NPC1KDM4EKMT2A | |
| SCHEMBL28024691 | 0.84 | KMT2A (0.52) | SMN1; SMN2ALDH1A1NPC1RECQLRAB9A | |
| SCHEMBL13490773 | 0.83 | KMT2A (0.45) | SMN1; SMN2ALDH1A1NPC1KDM4EKMT2A | |
| SCHEMBL8999717 | 0.78 | LMNA (0.47) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL1018491 | 0.77 | KMT2A (0.54) | SMN1; SMN2ALDH1A1NPC1KDM4ETP53 | |
| SCHEMBL22580252 | 0.76 | DYRK1A (0.40) | ALDH1A1KDM4ERECQLKMT2APOLB | |
| SCHEMBL778673 | 0.76 | MEN1 (0.52) | SMN1; SMN2ALDH1A1NPC1KDM4ETP53 | |
| SCHEMBL16479226 | 0.75 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL28255894 | 0.75 | TNFRSF1A (0.42) | ALDH1A1KDM4EKMT2APOLBLMNA | |
| SCHEMBL16479304 | 0.74 | OGG1 (0.56) | SMN1; SMN2ALDH1A1KMT2APOLBOGG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024078513-A1 | CONDENSED AZINES FOR TREATING CANCER | CHENGDU ANTICANCER BIOSCIENCE , LTD. (CN) | 2024-04-18 | — | — | WO | disclosed |