Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21722742 | 1.00 | MAPT (0.47) | MAPTSMN1; SMN2NPC1ALOX15RAB9A | |
| SCHEMBL30880780 | 1.00 | MAPT (0.47) | MAPTSMN1; SMN2NPC1ALOX15RAB9A | |
| SCHEMBL13100525 | 0.82 | POLB (0.58) | MAPTSMN1; SMN2IKBKBKDM4EGAA | |
| SCHEMBL13100535 | 0.78 | THRB (0.54) | MAPTSMN1; SMN2NPC1RAB9AIKBKB | |
| SCHEMBL8234022 | 0.78 | LMNA (0.62) | MAPTSMN1; SMN2NPC1ALOX15RAB9A | |
| SCHEMBL3461687 | 0.76 | NAMPT (0.49) | MAPTSMN1; SMN2NPC1ALOX15RAB9A | |
| SCHEMBL3463033 | 0.76 | NAMPT (0.49) | MAPTSMN1; SMN2NPC1ALOX15RAB9A | |
| SCHEMBL3456328 | 0.75 | MAPT (0.51) | MAPTSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL30880764 | 0.74 | POLB (0.59) | MAPTSMN1; SMN2NPC1ALOX15RAB9A | |
| SCHEMBL21722478 | 0.74 | POLB (0.59) | MAPTSMN1; SMN2NPC1ALOX15RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181092-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2024-05-03 | — | — | CN | disclosed |