Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.35 |
| ▸ | BTK | Q06187 | 3/20 | 0.34 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 4/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30881889 | 0.82 | IKBKB (0.38) | BTKCCNT1CDK9JAK2 | |
| SCHEMBL30881768 | 0.81 | IKBKB (0.37) | BTKCCNT1CDK9JAK2 | |
| SCHEMBL30881813 | 0.80 | BTK (0.37) | BTKABL1CCNT1CDK9JAK2 | |
| SCHEMBL30881772 | 0.78 | SCN9A (0.36) | BTKCCNT1CDK9JAK2 | |
| SCHEMBL30881816 | 0.78 | PDK2 (0.37) | BTKCCNT1CDK9JAK2 | |
| SCHEMBL30881810 | 0.76 | HPGD (0.36) | BTKCCNT1CDK9JAK2GSK3B | |
| SCHEMBL30881765 | 0.75 | IRAK4 (0.34) | BTKCCNT1CDK9JAK2 | |
| SCHEMBL30881673 | 0.71 | NTRK1 (0.34) | BTKCCNT1CDK9JAK2GRM2 | |
| SCHEMBL30881741 | 0.71 | KDR (0.40) | BTKJAK2 | |
| SCHEMBL30881752 | 0.70 | CHEK1 (0.43) | ATMBTKGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118026880-A | Aryl amide compound, pharmaceutical composition containing same and application thereof | 华东师范大学 | 2024-05-14 | — | — | CN | disclosed |