SCHEMBL3088243

SCHEMBL3088243

C=C[Si](C)(C)CC(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14600071 0.79
SCHEMBL8954744 0.77
SCHEMBL9357709 0.73 MCL1 (0.33)
SCHEMBL7770882 0.72 LMNA (0.35)
SCHEMBL11572327 0.70 ABCC4 (0.47)
SCHEMBL11355015 0.69 ABCC4 (0.45)
SCHEMBL29065871 0.67 FFAR3 (0.41)
SCHEMBL442427 0.67
SCHEMBL632284 0.67 FFAR3 (0.41)
Bicarbonate SCHEMBL9628099 0.67 LMNA (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0266076-B1 METHOD OF PRODUCING POLYDIORGANOSILOXANE GUM DOW CORNING CORPORATION (US) 1992-12-30 EP claimed
EP-0266075-B1 NEUTRALIZATION OF CATALYST IN POLYMERIZATION OF POLYDIORGANOSILOXANE DOW CORNING CORPORATION (US) 1992-12-09 EP claimed
US-4780519-A CONTROLLING WATER VAPOR PRESSURE; DEW POINT DOW CORNING CORPORATION (US) 1988-10-25 US claimed
EP-0266076-A2 Method of producing polydiorganosiloxane gum DOW CORNING CORPORATION (US) 1988-05-04 EP claimed
US-20160319079-A1 CROSS-LINKABLE SILICONE COMPOSITION WACKER CHEMIE AG (DE) 2016-11-03 US disclosed
EP-3083856-A1 CROSS-LINKABLE SILICONE COMPOSITION Wacker Chemie AG (DE) 2016-10-26 EP disclosed
CN-105940068-A Crosslinkable silicone composition 瓦克化学股份公司 2016-09-14 CN disclosed
WO-2015090374-A1 CROSS-LINKABLE SILICONE COMPOSITION WACKER CHEMIE AG (DE) 2015-06-25 WO disclosed
EP-1641871-B1 SINGLE-COMPONENT POLYORGANOSILOXANE (POS) COMPOSITIONS WHICH CROSSLINK TO FORM ELASTOMERS BY MEANS OF POLYCONDENSATION REACTIONS AT AMBIENT TEMPERATURE AND IN THE PRESENCE OF WATER, AND ELASTOMERS THUS OBTAINED BLUESTAR SILICONES FRANCE (FR) 2014-08-27 EP disclosed
US-20100234510-A1 TIN-FREE SINGLE-COMPONENT SILICONE COMPOSITIONS CROSSLINKABLE INTO ELASTOMERIC STATE BLUESTAR SILICONES FRANCE (FR) 2010-09-16 US disclosed
EP-2089461-A1 TIN-FREE SINGLE-COMPONENT SILICONE COMPOSITION WHICH CAN BE CROSSLINKED TO AN ELASTOMER Bluestar Silicones France (FR) 2009-08-19 EP disclosed
EP-1856191-B1 METHOD FOR THE PREPARATION OF ORGANOPOLYSILOXANE BY POLYMERIZATION AND REARRANGEMENT OF CYCLIC SILOXANES BLUESTAR SILICONES FRANCE (FR) 2008-09-03 EP disclosed
EP-0403400-A1 Functionalized silicon oil-based aqueous dispersion cross-linking to an elastomer by elimination of water RHONE-POULENC CHIMIE (FR) 1990-12-19 EP disclosed
EP-0367696-A1 Process for the preparation of alkoxy group-terminated diorganopolysiloxanes RHONE-POULENC CHIMIE (FR) 1990-05-09 EP disclosed
US-4766192-A MIXING POLYDIORGANOSILOXANE WITH PHOSPHORIC AND SILYLAMIDE COMPONENT DOW CORNING CORPORATION (US) 1988-08-23 US disclosed
US-4766191-A REDUCTION OF HYDROXY NUMBER BY MIXING WITH PHOSPHORIC COMPONENT AND SILYAMINE DOW CORNING CORPORATION (US) 1988-08-23 US disclosed
EP-0266075-A2 Neutralization of catalyst in polymerization of polydiorganosiloxane DOW CORNING CORPORATION (US) 1988-05-04 EP disclosed
EP-0265779-A2 Improved silicone extrusion stock DOW CORNING CORPORATION (US) 1988-05-04 EP disclosed
US-4719276-A USING A TRIHYDROCARBYLSILYLCARBOXYLATE DOW CORNING CORPORATION (US) 1988-01-12 US disclosed
US-4701491-A BLEND OF POLYSILOXANE AND REINFORCING SILICA FILLERS DOW CORNING CORPORATION (US) 1987-10-20 US disclosed