Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | PRKACG | P22612 | 1/20 | 0.39 |
| ▸ | PRKACB | P22694 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | RHEB | Q15382 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30883114 | 0.88 | LMNA (0.38) | SRCPRKACAPRKACGPRKACBGSR | |
| SCHEMBL7213488 | 0.82 | PPARG (0.48) | SRCLMNAGAAHPGDTSHR | |
| SCHEMBL30883100 | 0.77 | NOD2 (0.47) | CYP2C19LMNAGAAMEN1KMT2A | |
| SCHEMBL16818436 | 0.77 | BRD4 (0.50) | CYP2C19LMNAMEN1KMT2ACYP2C9 | |
| SCHEMBL26620218 | 0.73 | PPARG (0.47) | LMNAGAAHPGDTSHR | |
| SCHEMBL30296816 | 0.73 | PPARG (0.47) | LMNAGAAHPGDTSHR | |
| SCHEMBL16235830 | 0.71 | PPARG (0.46) | SRCLMNAGAAHPGDTSHR | |
| SCHEMBL7214465 | 0.70 | PPARG (0.46) | SRCLMNAGAAHPGDTSHR | |
| SCHEMBL3535429 | 0.69 | PPARG (0.68) | — | |
| SCHEMBL27732238 | 0.68 | PPARG (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916241-A | Spiro compounds | 阿斯利康(瑞典)有限公司 | 2024-04-19 | — | — | CN | disclosed |