Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 5/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7214149 | 0.85 | NOD2 (0.62) | NOD2NOD1SMN1; SMN2POLBTSHR | |
| SCHEMBL26620160 | 0.79 | NOD1 (0.64) | NOD2NOD1TSHRGAAMAPT | |
| SCHEMBL30883111 | 0.77 | SRC (0.39) | TSHRGAACYP2C19LMNAMEN1 | |
| SCHEMBL30883114 | 0.74 | LMNA (0.38) | TDP1TSHRGAACYP2C19NPSR1 | |
| SCHEMBL16254657 | 0.73 | NOD1 (0.46) | NOD2NOD1POLBTSHRMAPT | |
| SCHEMBL16852961 | 0.72 | SMN1; SMN2 (0.39) | NOD2NOD1SMN1; SMN2TDP1MAPT | |
| SCHEMBL29189067 | 0.72 | NOD2 (0.46) | NOD2NOD1SMN1; SMN2POLBTDP1 | |
| SCHEMBL30436082 | 0.72 | NOD2 (0.46) | NOD2NOD1SMN1; SMN2POLBTDP1 | |
| SCHEMBL16818422 | 0.71 | F10 (0.48) | NOD2NOD1POLBTDP1TSHR | |
| SCHEMBL16818895 | 0.70 | NOD1 (0.43) | NOD2NOD1TSHRMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916241-A | Spiro compounds | 阿斯利康(瑞典)有限公司 | 2024-04-19 | — | — | CN | disclosed |