Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 3/20 | 0.52 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30883148 | 0.85 | FFAR4 (0.52) | XPO1MAPTHTTSMN1; SMN2MEN1 | |
| SCHEMBL3718118 | 0.81 | ADRA1B (0.48) | XPO1ERAP1HTTALDH1A1TSHR | |
| SCHEMBL30883140 | 0.79 | SERPINE1 (0.61) | MAPTHTTSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL29204817 | 0.77 | XPO1 (0.80) | XPO1ERAP1MAPTHTTHPGD | |
| SCHEMBL23632910 | 0.75 | PPARD (0.66) | ALDH1A1 | |
| SCHEMBL2304981 | 0.75 | MAPT (0.61) | MAPTSMN1; SMN2TP53GAA | |
| SCHEMBL2303406 | 0.74 | P2RX1 (0.62) | XPO1MAPTHTTSMN1; SMN2TP53 | |
| SCHEMBL211403 | 0.74 | ADRB1 (0.56) | MAPTHTTSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL2303364 | 0.74 | TP53 (0.56) | XPO1MAPTHTTSMN1; SMN2HPGD | |
| SCHEMBL13261277 | 0.73 | GPR119 (0.59) | MAPTHTTSMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964578-A | Non-covalent CRM1 inhibitor and preparation method and application thereof | 四川大学 | 2024-05-03 | — | — | CN | disclosed |