Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2851943 | 0.92 | THRA (0.49) | ALDH1A1SMN1; SMN2L3MBTL1NPSR1KMT2A | |
| SCHEMBL5861984 | 0.92 | THRA (0.49) | ALDH1A1SMN1; SMN2L3MBTL1NPSR1KMT2A | |
| SCHEMBL18931167 | 0.91 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2L3MBTL1NPSR1KMT2A | |
| SCHEMBL2850836 | 0.87 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2L3MBTL1NPSR1KMT2A | |
| SCHEMBL814500 | 0.85 | KDM4E (0.47) | ALDH1A1SMN1; SMN2L3MBTL1NPSR1KMT2A | |
| SCHEMBL3920762 | 0.85 | MAPT (0.54) | ALDH1A1SMN1; SMN2L3MBTL1NPSR1KMT2A | |
| SCHEMBL12772150 | 0.82 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2L3MBTL1NPSR1KMT2A | |
| SCHEMBL815507 | 0.81 | KDM4E (0.46) | ALDH1A1SMN1; SMN2L3MBTL1NPSR1KMT2A | |
| SCHEMBL38656301 | 0.80 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2L3MBTL1NPSR1KMT2A | |
| SCHEMBL24075852 | 0.80 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2L3MBTL1NPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964652-A | Tetradentate phenol ether ligand-metal complex derived from naphthol, preparation method and olefin polymerization method | 中国科学院大连化学物理研究所 | 2024-05-03 | — | — | CN | disclosed |