SCHEMBL24075852

SCHEMBL24075852

CC(C)(C)c1ccc(OC[Si](COc2ccc(C(C)(C)C)cc2Br)(C(C)(C)C)C(C)(C)C)c(Br)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
SMN1; SMN2 Q16637 4/20 0.48
KMT2A Q03164 4/20 0.48
NPSR1 Q6W5P4 4/20 0.48
MEN1 O00255 3/20 0.48
NPC1 O15118 1/20 0.48
HTT P42858 1/20 0.48
RAB9A P51151 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
ALOX15 P16050 1/20 0.47
HSD17B10 Q99714 1/20 0.47
MAPT P10636 6/20 0.44
TSHR P16473 2/20 0.44
MAPK1 P28482 2/20 0.44
LMNA P02545 1/20 0.44
CASP3 P42574 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
POLB P06746 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30118971 1.00 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2KMT2ANPSR1MEN1
SCHEMBL25672611 0.81 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2KMT2ANPSR1MEN1
SCHEMBL30118970 0.81 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2KMT2ANPSR1MEN1
SCHEMBL19816836 0.81 PKM (0.50) ALDH1A1SMN1; SMN2KMT2AMEN1NPC1
SCHEMBL3920762 0.80 MAPT (0.54) ALDH1A1SMN1; SMN2KMT2ANPSR1MEN1
SCHEMBL30883282 0.80 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2KMT2ANPSR1MEN1
SCHEMBL12772150 0.77 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2KMT2ANPSR1MEN1
SCHEMBL18931167 0.75 ALDH1A1 (0.49) ALDH1A1SMN1; SMN2KMT2ANPSR1MEN1
SCHEMBL38656301 0.75 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2KMT2ANPSR1MEN1
SCHEMBL2846243 0.74 KMT2A (0.49) ALDH1A1SMN1; SMN2KMT2ANPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230235099-A1 CATALYST SYSTEMS AND PROCESSES FOR PRODUCING POLYETHYLENE USING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2023-07-27 US disclosed
US-20230203216-A1 CATALYST SYSTEMS AND PROCESSES FOR PRODUCING POLYETHYLENE USING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2023-06-29 US disclosed
US-20230203216-A1 CATALYST SYSTEMS AND PROCESSES FOR PRODUCING POLYETHYLENE USING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2023-06-29 US disclosed
WO-2021243211-A1 CATALYST SYSTEMS AND PROCESSES FOR PRODUCING POLYETHYLENE USING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2021-12-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230203216-A1 CATALYST SYSTEMS AND PROCESSES FOR PRODUCING POLYETHYLENE USING THE SAME MRPL21, PGLS, PARG ALDH1A1 2223/4885SMN1; SMN2 4311/4885KMT2A 2307/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.