Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ECE1 | P42892 | 1/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16366772 | 0.85 | CYP2D6 (0.54) | LMNAKMT2ATDP1ALDH1A1NPC1 | |
| SCHEMBL6568637 | 0.85 | CYP2D6 (0.54) | LMNAKMT2ATDP1ALDH1A1NPC1 | |
| SCHEMBL13767683 | 0.84 | ALDH1A1 (0.58) | LMNAKMT2ATDP1ALDH1A1MAPT | |
| (Chloromethyl)Benzene SCHEMBL10947727 | 0.82 | ALDH1A1 (0.61) | LMNAKMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL5363086 | 0.82 | ALDH1A1 (0.63) | LMNAKMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL22946419 | 0.81 | L3MBTL1 (0.57) | LMNAKMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL30827513 | 0.80 | ALDH1A1 (0.78) | LMNAKMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL1628833 | 0.80 | ALDH1A1 (0.78) | LMNAKMT2ATDP1ALDH1A1MAPT | |
| Ammonia Solution, Strong SCHEMBL27461059 | 0.79 | ALDH1A1 (0.76) | LMNAKMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL29458655 | 0.79 | ALDH1A1 (0.76) | LMNAKMT2ATDP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11963964-B2 | Small molecules for mouse satellite cell proliferation | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11963964-B2 | Small molecules for mouse satellite cell proliferation | MKI67, MYLK2, MYH2 | LMNA 1250/4885KMT2A 1908/4885TDP1 1865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.