Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989638 | 0.93 | KMT2A (0.46) | MAPTRAB9ANPC1HTTSMN1; SMN2 | |
| SCHEMBL344615 | 0.87 | TSHR (0.55) | RAB9ANPC1HTTSMN1; SMN2PRKCA | |
| SCHEMBL3074456 | 0.86 | PRKCA (0.45) | MAPTRAB9ANPC1HTTSMN1; SMN2 | |
| SCHEMBL2962888 | 0.84 | CA12 (0.48) | MAPTRAB9ASMN1; SMN2CYP4F2CYP4A11 | |
| SCHEMBL10884435 | 0.83 | PRKCA (0.42) | MAPTRAB9ANPC1HTTSMN1; SMN2 | |
| SCHEMBL7181542 | 0.83 | PRKCA (0.53) | MAPTRAB9ANPC1HTTSMN1; SMN2 | |
| SCHEMBL5375275 | 0.81 | MAPT (0.48) | MAPTRAB9ANPC1HTTSMN1; SMN2 | |
| SCHEMBL2128862 | 0.81 | ALDH1A1 (0.49) | MAPTRAB9ANPC1PRKCAPRKCD | |
| SCHEMBL2185343 | 0.80 | KMT2A (0.48) | MAPTRAB9ANPC1HTTSMN1; SMN2 | |
| SCHEMBL3358299 | 0.80 | MAPT (0.44) | MAPTRAB9ANPC1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799892-B2 | Method of making polybutylene terephthalate and compositions and articles comprising the same | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-09-21 | — | — | US | claimed |
| EP-0379761-A1 | Unsaturated polyesters and their preparation | ARCO Chemical Technology, L.P. (US) | 1990-08-01 | — | — | EP | claimed |
| CN-1498203-A | Sophthalic acid glycol ester solution | ��Ļ���Ű˾ | 2004-05-19 | — | — | CN | disclosed |
| US-4045527-A | MIXING POLYTETRAMETHYLENE GLYCOL RESIN PREPOLYMER WITH A DIISOCYANATE, A METAL SALT CURING CATALYST, AND A TETRAALKANOL AMINE CURING AGENT | HITCO (US) | 1977-08-30 | — | — | US | disclosed |
| US-3953387-A | CONTAINING A CARBOXYLIC ACID AND A HINDERED PHENOL | ATLANTIC RICHFIELD COMPANY (US) | 1976-04-27 | — | — | US | disclosed |