SCHEMBL2185343

SCHEMBL2185343

CCCC(O)OC(=O)c1cccc(C(=O)O)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.48
SMN1; SMN2 Q16637 4/20 0.43
MRGPRX4 Q96LA9 2/20 0.43
TP53 P04637 1/20 0.43
PKM P14618 1/20 0.43
NFKB1 P19838 1/20 0.43
NFKB2 Q00653 1/20 0.43
RELA Q04206 1/20 0.43
PRKCA P17252 1/20 0.41
PRKCD Q05655 1/20 0.41
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
MAPT P10636 1/20 0.40
HTT P42858 1/20 0.40
NR1H4 Q96RI1 1/20 0.40
MITF O75030 1/20 0.40
PAX8 Q06710 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3074456 0.94 PRKCA (0.45) SMN1; SMN2PRKCAPRKCDNPC1RAB9A
SCHEMBL3877617 0.90 PLA2G4B (0.45) KMT2ATP53NR1H4PLA2G4BALDH1A1
SCHEMBL9989638 0.88 KMT2A (0.46) KMT2ASMN1; SMN2MRGPRX4TP53PKM
SCHEMBL525355 0.85 LMNA (0.53) KMT2ASMN1; SMN2TP53PRKCANPC1
Adipic Acid SCHEMBL8967488 0.84 LTB4R (0.47) KMT2ANR1H4PLA2G4BALDH1A1
SCHEMBL2061233 0.84 MAPT (0.49) KMT2ATP53MAPTCA12CA1
Terephthalic Acid SCHEMBL8439001 0.84 MAPT (0.49) KMT2ATP53MAPTCA12CA1
SCHEMBL4946489 0.84 PRKCA (0.61) KMT2ASMN1; SMN2MRGPRX4TP53PKM
SCHEMBL27886416 0.84 KMT2A (0.47) KMT2ASMN1; SMN2MRGPRX4TP53PKM
SCHEMBL6227202 0.82 KMT2A (0.46) KMT2ASMN1; SMN2MRGPRX4TP53PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109705794-B Low-viscosity UV/moisture dual-curing polyurethane hot melt adhesive and preparation method thereof 重庆中科力泰高分子材料股份有限公司 2022-10-04 CN claimed
CN-118251523-A Flooring product with polyester-based coated facing fibers 美国阿拉丁制造公司 2024-06-25 CN disclosed
CN-117561015-A Biodegradable product and method for producing the same 美国阿拉丁制造公司 2024-02-13 CN disclosed
CN-116496744-A Polyester hot melt adhesive with low melt viscosity and quick solidification and preparation method thereof 李思斌 2023-07-28 CN disclosed
CN-116194808-A Removal of color from polymeric materials 美国阿拉丁制造公司 2023-05-30 CN disclosed
CN-115678059-A Heat-shrinkable polyester label film, method for producing same, and container 远东新世纪股份有限公司 2023-02-03 CN disclosed
CN-109705794-B Low-viscosity UV/moisture dual-curing polyurethane hot melt adhesive and preparation method thereof 重庆中科力泰高分子材料股份有限公司 2022-10-04 CN disclosed
US-20130302568-A1 FILM AND METHOD FOR PRODUCING FILM FUJIFILM CORP (JP) 2013-11-14 US disclosed
US-8501065-B2 Film and method for producing film FUJIFILM CORPORATION (JP) 2013-08-06 US disclosed
US-20110177289-A1 FILM AND METHOD FOR PRODUCING FILM FUJIFILM CORPORATION (JP) 2011-07-21 US disclosed
US-6692803-B2 GAS TRANSMISSION RATE OF 15.0 OR LESS FOR NITROGEN GAS AND AN AVERAGE THICKNESS OF APPROXIMATELY 20.0 MILS. NIKE, INC. 2004-02-17 US disclosed
US-6652940-B2 Membrane including a polyesterurethane copolymer, the membrane having low nitrogen gas transmission rate and given thickness; variety of end-uses, such as fuel lines, in-line skate wheels, cushioning in prosthetics; containers NIKE, INC. 2003-11-25 US disclosed
US-20020048643-A1 Membranes of polyurethane based materials including polyester polyols BONK HENRY W (US) 2002-04-25 US disclosed
US-20020045048-A1 Membranes of polyurethane based materials including polyester polyols BONK HENRY W (US) 2002-04-18 US disclosed
US-20020034598-A1 Membranes of polyurethane based materials including polyester polyols BONK HENRY W (US) 2002-03-21 US disclosed
US-6321465-B1 CUSHIONING DEVICE FOR A SHOE COMPRISING A SEALED, INFLATED FLEXIBLE POLYESTERURETHANE MEMBRANE HAVING A GAS TRANSMISSION RATE OF ABOUT 15 OR LESS FOR NITROGEN GAS. NIKE, INC. 2001-11-27 US disclosed
US-6013340-A MEMBRANES WHICH, UNDER CERTAIN EMBODIMENTS, SERVE TO SELECTIVELY CONTROL THE DIFFUSION OF GASES THROUGH THE MEMBRANE; CUSHIONING DEVICES USEFUL IN FOOTWEAR NIKE, INC. (US) 2000-01-11 US disclosed
EP-0884960-A4 MEMBRANES OF POLYURETHANE BASED MATERIALS INCLUDING POLYESTER POLYOLS NIKE INTERNATIONAL LTD (US) 1999-12-22 EP disclosed
EP-0884960-A1 MEMBRANES OF POLYURETHANE BASED MATERIALS INCLUDING POLYESTER POLYOLS NIKE INTERNATIONAL LTD (US) 1998-12-23 EP disclosed
WO-1996039885-A1 MEMBRANES OF POLYURETHANE BASED MATERIALS INCLUDING POLYESTER POLYOLS NIKE, INC. (US) 1996-12-19 WO disclosed