Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 12/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30885423 | 0.94 | STING1 (0.51) | STING1MAPTNOTUMMTNR1AMTNR1B | |
| SCHEMBL30885377 | 0.92 | STING1 (0.49) | STING1MAPTNOTUMMPOKMT2A | |
| SCHEMBL30885374 | 0.90 | STING1 (0.48) | STING1MAPTADRB3SMN1; SMN2 | |
| SCHEMBL30885428 | 0.90 | STING1 (0.55) | STING1MAPTNOTUMMTNR1AMTNR1B | |
| SCHEMBL30885381 | 0.89 | STING1 (0.52) | STING1 | |
| SCHEMBL30885442 | 0.85 | STING1 (0.46) | STING1MAPTMPOSMN1; SMN2 | |
| SCHEMBL30885434 | 0.84 | STING1 (0.53) | STING1MAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL30885446 | 0.83 | STING1 (0.50) | STING1 | |
| SCHEMBL30885399 | 0.83 | STING1 (0.52) | STING1MAPTMPOKDM4EALDH1A1 | |
| SCHEMBL30885460 | 0.83 | STING1 (0.45) | STING1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756698-A | Urea compound and medical application thereof as STING inhibitor | 中国药科大学 | 2024-03-26 | — | — | CN | disclosed |