Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NHERF1 | O14745 | 2/20 | 0.51 |
| ▸ | STING1 | Q86WV6 | 9/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.42 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30885402 | 0.95 | NHERF1 (0.48) | NHERF1STING1TRPV1KMT2ANTRK1 | |
| SCHEMBL30885432 | 0.91 | NHERF1 (0.52) | NHERF1STING1TRPV1KMT2ANTRK1 | |
| SCHEMBL30885381 | 0.90 | STING1 (0.52) | NHERF1STING1NTRK1SNCA | |
| SCHEMBL30885374 | 0.89 | STING1 (0.48) | STING1TRPV1GRIK1SNCA | |
| SCHEMBL30885442 | 0.85 | STING1 (0.46) | STING1TRPV1GRIK1SNCA | |
| SCHEMBL30885446 | 0.85 | STING1 (0.50) | NHERF1STING1NTRK1GRIK1SNCA | |
| SCHEMBL30885392 | 0.84 | STING1 (0.49) | NHERF1STING1NTRK1GRIK1SNCA | |
| SCHEMBL30885409 | 0.83 | STING1 (0.48) | NHERF1STING1NTRK1GRIK1SNCA | |
| SCHEMBL30885375 | 0.82 | STING1 (0.54) | NHERF1STING1GRIK1SNCA | |
| SCHEMBL30885439 | 0.81 | STING1 (0.44) | NHERF1STING1TRPV1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756698-A | Urea compound and medical application thereof as STING inhibitor | 中国药科大学 | 2024-03-26 | — | — | CN | disclosed |