Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 9/20 | 0.48 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.41 |
| ▸ | GOT1 | P17174 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30885442 | 0.95 | STING1 (0.46) | STING1ANO1MAPTSMN1; SMN2TRPV1 | |
| SCHEMBL30885433 | 0.90 | STING1 (0.53) | STING1MAPTSMN1; SMN2ADRB3 | |
| SCHEMBL30885461 | 0.89 | NHERF1 (0.51) | STING1TRPV1GRIK1SNCA | |
| SCHEMBL30885402 | 0.85 | NHERF1 (0.48) | STING1SMN1; SMN2TRPV1GRIK1SNCA | |
| SCHEMBL30885423 | 0.84 | STING1 (0.51) | STING1MAPT | |
| SCHEMBL30885377 | 0.83 | STING1 (0.49) | STING1MAPT | |
| SCHEMBL30885428 | 0.82 | STING1 (0.55) | STING1MAPT | |
| SCHEMBL30885460 | 0.81 | STING1 (0.45) | STING1MAPT | |
| SCHEMBL30885432 | 0.80 | NHERF1 (0.52) | STING1MAPTTRPV1GRIK1SNCA | |
| SCHEMBL30885381 | 0.79 | STING1 (0.52) | STING1GOT1SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756698-A | Urea compound and medical application thereof as STING inhibitor | 中国药科大学 | 2024-03-26 | — | — | CN | disclosed |